BIOSC 30 Genomics Theory

  • 4 units, 3 hours lecture, 3 hours laboratory (GRorP/NP)
  • Recommended preparation:BIOL 10 or equivalent
  • Acceptable for credit: CSU,UC

Introduction to genetics and genomic technologies: Principles of genetics and data collection (DNA and RNA structure, mitochondrial DNA, nucleic acid replication, protein synthesis, mitosis-meiosis, Mendelian principles, mutation, molecular character alignment, evolution and phylogenetic reconstruction), combined with data handling (bioinformatics mining using GenBank data), and scientific writing; includes guest speakers and on-site tours of genomics institutions and labs.

Student Learning Outcomes for BIOSC 30:

  • Discuss the new trends of the DNA industry, debate the pros and cons behind these changes, and relate this to the future of DNA sequencing, analysis and application.
  • Describe DNA, RNA, protein synthesis and gene expression and relate this to modern DNA analysis
  • Demonstrate working knowledge of genomics equipment including PCR, gel electrophoresis, microrobotic instruments, DNA shearing devices and fragment analyzer.

BIOSC 31 Advanced Genomics Theory

  • 4 units, 3 hours lecture, 3 hours laboratory (GRorP/NP)
  • Recommended preparation:BIOL 10 or equivalent
  • Acceptable for credit: CSU,UC

Practice and theory of laboratory techniques: DNA extraction, polymerase chain reaction (PCR), primer design, DNA shearing, cloning, data handling, laboratory safety and good laboratory techniques, col- lection of new DNA data for publication in a scientific journal.

Student Learning Outcomes for BIOSC 31: 

  • Demonstrate good laboratory techniques
  • Describe theory and rationale behind good laboratory techniques

BIOSC 50 Genetic Diseases

  • 4 units, 4 hours lecture (GRorP/NP)
  • Acceptable for credit: CSU,UC
  • AA/AS Area 1

Survey of common genetic diseases which result from various mutations and chromosomal aberrations: Genetic modifiers and epigenetic factors as they relate to disease; review of basic Mendelian principles.

Student Learning Outcomes for BIOSC 50:

  • Describe the stages meiosis as well as chromosomal aberrations and the causal relationship of the latter to genetic disease
  • Apply knowledge of genetic principles to analyze variations in inheritance
  • Explain the biochemical basis for mutation, including point mutation, duplication substitution, and deletion
  • Debate the ethics of genetic disease treatment and the rationale for genetic counseling
  • Identify signs, symptoms, and treatments for a broad range of common genetic diseases

BIOSC 59 My Genome

  • 3 units, 3 hours
  • Acceptable for credit: CSU

Survey of genotypes, phenotypes and ancestry assessed through a student’s personal genome.

Student Learning Outcomes for BIOSC 59 (currently being revised)

  • Students will demonstrate comprehension of the concepts of ethics in genomics
  • Students will utilize the principles of probability as related to their genome and the genomes of their potential offspring.