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Courses


Course Number: BIOSC 1 
Introduction to Microscopy
Units: 4
Class:  3 hours lecture, 3 hours laboratory (GR or P/NP)
Recommended preparation: CIS 200 or 205 or equivalent, and Engl 201A
Acceptable for credit: CSU
Description: General survey of current microscopy technologies, including brightfield, epifluorescence, confocal, and electron microscopy: Operation of software, specimen preparation, live-cell imaging technologies, artifacts and troubleshooting, and careers in microscopy; laboratory includes hands-on experience with brightfield and digital fluorescence microscopes, and image processing using specialized software.  0430.00
 

Course Number: BIOSC 2
Theory and Practice of Optical Microscopy
Units: 5
Class:  4 hours lecture, 3 hours laboratory (GR or P/NP)
Acceptable for credit: CSU
Description: Comprehensive survey of microscopy, from brightfield, epifluorescence, confocal, multiphoton, and scanning and transmission electron microscopes, to the newest technologies: Specimen preparation (both live and fixed), plus digital-image processing; laboratory includes hands-on experience with DIC, phase and epifluorescence microscopes, plus tissue culture, and Adobe Photoshop.  0430.00
 

Course Number: BIOSC 3
Fluorescence Microscopy in Bioscience
Units: 4
Class:  4 hours lecture (GR or P/NP)
Pre-requisite: Biosc 2
Acceptable for credit: CSU
Description: Theory and practice of flourescence microscopy: FRAP, FCS, FLIM, and FRET; artifacts and troubleshooting; and survey of employment opportunities using latest technologies.  0430.00
 

Course Number: BIOSC 4
Advanced Microscopy Research Practicum
Units: 1-3
Class:  3-9 hours laboratory (GR or P/NP)
Pre-requisite: Biosc 2
Co-requisite: Biosc 3
Acceptable for credit: CSU
Course study under this section may be repeated two times for a maximum of 3 units.
Description: Guided lab project using widefield fluorescence and/or confocal microscopy plus cell culture, IHC and digital imaging: Image acquisition, processing and analysis. 0430.00
 

Course Number: BIOSC 5
Good Laboratory Practices
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 2
Recommended preparation: Biol 10, and Biosc 1, and CIS 200 or 205, and Engl 201B
Acceptable for credit: CSU
Description: Introduction to good laboratory practices: EPA and FDA regulatory requirements for research and testing of products, protocols and standard operating procedures (SOPs) for design of experiments utilizing sterile and basic laboratory techniques; accurate recording of observations, analysis of data, and reporting of experiment results; safety, instrumentation, and equipment maintenance; and utilization of word processing, spreadsheet, and presentation graphics to document and present project/experiment results.  0430.00
 

Course Number: BIOSC 6
Survey of Biotech Industry
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 2
Acceptable for credit: CSU
Description: Survey of the local biotech industry: History, structure, and product pipelines of local biotech companies.  0430.00
 

Course Number: BIOSC 7
Practical Mammalian Cell Culture
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Co-requisite: Biosc 2
Acceptable for credit: CSU
Description: Introduction to the basics of mammalian cell culture: Sterile technique, media preparation, and cell counting; cell lines, including adherent and non- adherent cells; response to infections.  0430.00
 

Course Number: BIOSC 8
Immunohistochemistry
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Co-requisite: Biosc 2
Acceptable for credit: CSU
Description: Principles and protocols in immunohistochemistry and transfection of mammalian cells: Overview of common transfection techniques, standard immunohistochemistry protocols, antibodies, troubleshooting, and emergent technologies.  0430.00
 

Course Number: BIOSC 9
General Histology 
Units: 5
Class:  4 hours lecture, 3 hours laboratory (GR or P/NP)
Pre-requisite: Biol 1A or 2 or 10 or 20A or 24
Acceptable for credit: CSU, UC
Description: Survey of plant and animal histology with an emphasis on human histology: Overview of cells, cellular organelles; plant, animal, and human tissues and relationship to organ system.  0430.00
 

Course Number: BIOSC 10
Fluorescence Microscopy Laboratory
Units: 3-6
Class:  9-18 hours laboratory (GR or P/NP)
Co-requisite: Biosc 2
Acceptable for credit: CSU
Description: Optical microscopy laboratory: Training in the practical use of digital imaging systems and operating a large variety of widefield fluorescence imaging systems and several confocal microscopes. Post-acquisition processing will also be performed on a variety of platforms.  0430.00
 

Course Number: BIOSC 11
Lab Safety and Ethics
Units: .5
Class:  .5 hours lecture (GR or P/NP)
Co-requisite: Biosc 2
Acceptable for credit: CSU
Description: Overview of safety procedures in life sciences labs and ethical considerations in current life sciences research: Laboratory safety protocols and procedures used with flammables, chemicals, radiation, microbes and biohazards; documentation, controls, fraud, plagiarism, intellectual property, authorship and other issues in biological research.  0430.00
 

Course Number: BIOSC 12
Seminar in Microscopy Internship
Units: .5
Class:  .5 hours lecture (GR or P/NP)
Co-requisite: Coped 484B
Acceptable for credit: CSU
Description: Study of the specific competencies required in the Microscopy Internship program: Assessment, development, practicum, and evaluation of individual skills in a microscopy work setting. Course accompanies COPED 484B, Occupational Work Experience in Bioscience, and provides students with the additional tools needed to have a successful and productive internship experience.  0430.00
 

Course Number: BIOSC 13
Research Design
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 3
Acceptable for credit: CSU
Description: Introduction to biological research design: Investigation and development of a research question, and crafting a research plan to answer the question; literature searches and other research tools, critique of published research, and presentation of a research proposal.  0430.00
 

Course Number: BIOSC 14
Digital-Imaging Software for Microscopy
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 3
Acceptable for credit: CSU
Description: Advanced-level training in digital-imaging software relevant to bioscience microscopy: Image J, Metamorph, Photoshop, NIS Elements, ImagePro, Axiovision, Q Imaging, and others; theory of digital imaging, quantitative imaging, manual and automatic morphometric measurements, 6D analysis, troubleshooting.  0430.00
 

Course Number: BIOSC 15
Live-Cell Imaging
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 3
Acceptable for credit: CSU
Description: Principles and protocols for imaging of live cells: Transfection with fluorescent proteins (including GFP), perfusion techniques, imaging chambers, time-lapse videomicroscopy, 4D-imaging software, current imaging systems, and emergent technologies. 0430.00
 

Course Number: BIOSC 16
Advanced Confocal Microscopy Laboratory
Units: 2
Class:  6 hours laboratory (GR or P/NP)
Co-requisite: Biosc 3
Acceptable for credit: CSU
Description: Advanced optical microscopy laboratory: Extensive hands-on training in fully motorized widefield microscopes, a spectral-imaging confocal microscope, and a spinning-disc confocal microscope. Post- acquisition processing will be performed on multiple software platforms.  0430.00
 

Course Number: BIOSC 20
Emerging Technologies in Microscopy
Units: 1
Class:  1 hour lecture (GR or P/NP)
Recommended preparation: Biosc 2
Acceptable for credit: CSU
Description: Seminar series: Guest speakers on latest developments in microscopy and digital imaging.  0430.00