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Courses


Course Number: BIOSC 30
Genomics Theory
Units: 4
Class:  3 hours lecture, 3 hours laboratory (GR or P/NP)
Pre-requisite: Biol 10 or equivalent
Acceptable for credit: CSU
Description: Introduction to genetics and genomic technologies: Principles of genetics and data collection (DNA and RNA structure, mitochondrial DNA, nucleic acid replication, protein synthesis, mitosis-meiosis, Mendelian principles, mutation, molecular character alignment, evolution and phylogenetic reconstruction), combined with data handling (bioinformatics mining using GenBank data), and scientific writing; includes guest speakers and on- site tours of genomics institutions and labs.  0430.00
 

Course Number: BIOSC 31
Practical Genomics
Units: 4
Class:  3 hours lecture, 3 hours laboratory (GR or P/NP)
Pre-requisite: Biol 10 or equivalent
Acceptable for credit: CSU
Description: Introduction to practical genomics: Laboratory techniques such as DNA extraction, polymerase chain reaction (PCR), primer design, DNA shearing, cloning, and data handling of raw, newly obtained DNA data with emphasis on laboratory safety and sample handling to avoid contamination; collection of new DNA data for publication in a scientific journal; includes guest speakers and on-site tours of genomics institutions and labs.  0430.00
 

Course Number: BIOSC 32
Good Laboratory Practices in Genomics
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR)
Co-requisite: Biosc 30
Recommended preparation: Biol 10, and CIS 200 or 205
Acceptable for credit: CSU
Description: Introduction to good laboratory practices in genomics: EPA and FDA regulatory protocols and standard operating procedures for designing experiments; recording observations, analyzing and reporting results; safety, instrumentation, and equipment maintenance; and documenting and presenting project/experiment results.  0430.00
 

Course Number: BIOSC 33
Research Design in Genomics
Units: 1
Class:  1 hour lecture (GR or P/NP)
Co-requisite: Biosc 30
Acceptable for credit: CSU
Description: Introduction to research design: Biological research including investigation and development of a research question, and crafting a research plan to answer the question; literature searches and other research tools, critique of published research, and presentation of a research proposal.  0430.00
 

Course Number: BIOSC 34
Writing for the Scientific Journal
Units: 1-3
Class:  1-3 hours lecture (GR or P/NP)
Pre-requisite: Biol 36 and Biosc 30
Recommended preparation: Engl 1A
Acceptable for credit: CSU
Description: Introduction to writing for the scientific journal: Writing, editing, and reviewing other’s work; comparison of private publications with that of society-based and open-access publications; using the Internet for data collection and analysis, copyright issues, and data-based referencing such as PubMed Central; deposition of data in archived web sites such as GenBank; writing a scientific manuscript, editing, the peer-review process, and interpretation of reviews. 0430.00
AA/AS area 4d (minimum of 3 units)
 

Course Number: BIOSC 35
Micro-Robotics in DNA Sequencing
Units: 5
Class:  4 hours lecture, 3 hours laboratory (GR or P/NP)
Acceptable for credit: CSU
Description: Introduction to use of small-scale instrumentation involved in DNA sequencing: Bar coding and project management, sterile technique and reagents and enzymes in DNA sequencing, software management techniques in capillary sequencers and auxiliary instrumentation software, and future of DNA sequencing.  0430.00
 

Course Number: BIOSC 36
Scientific Presentation
Units: 3
Class:  3 hours lecture (GR or P/NP)
Acceptable for credit: CSU
Description: Introduction to visual and oral communication skills necessary for presenting scientific research to the public: Developing a proposal, abstract, and poster presentation; emphasis on preparatory work such as the literature review, organizational and oral presentation skills, and ethics in presentations.  0430.00
 

Course Number: BIOSC 37
Principles of Long Polymerase Chain Reaction (PCR)
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Recommended preparation: Biosc 31
Acceptable for credit: CSU
Description: Theoretical and practical methodology for the use of the polymerase chain reaction (PCR): Strategies for optimizing long-PCR performance including amplification of long fragments of DNA.  0430.00
 

Course Number: BIOSC 38
Real-Time Polymerase Chain Reaction (PCR)
Units: 2
Class:  1 hour lecture, 3 hours laboratory (GR or P/NP)
Pre-requisite: Biosc 37
Acceptable for credit: CSU
Description: Real-time PCR in a laboratory setting: Issues and protocols for troubleshooting, analyzing and interpreting data, and application for next-generation DNA sequencing library preparation. 0430.00
 

Course Number: BIOSC 40
DNA Shearing Techniques for Shotgun Sequencing in Genomics
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Acceptable for credit: CSU
Description: Shotgun sequencing and techniques using Covaris and the Hydroshear in DNA preparation.  0430.00
 

Course Number: BIOSC 41
Microfluidic Electrophoresis
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Recommended preparation: Biosc 31
Acceptable for credit: CSU
Description: Modern techniques that replace gel electrophoresis for separating nucleic-acid samples: Troubleshooting and use of appropriate instrumentation such as the Bioanalyzer.  0430.00
 

Course Number: BIOSC 43
Flow Cytometry
Units: 1
Class:  .5 hours lecture, 1.5 hours laboratory (GR or P/NP)
Acceptable for credit: CSU
Description: Introduction to flow cytometry: Preparations for and applications of DNA-sequencing procedures.  0430.00
 

Course Number: BIOSC 48NA-TZ
Selected Topics in Biosciences
Units: .5-9
Class:  0-9 hours lecture, 0-27 hours laboratory (GR or P/NP)
Acceptable for credit: CSU
Description: See section on Selected Topics.  0430.00
 

Course Number: BIOSC 49
Independent Study in Biosciences
Units: .5-5
Class:  (GR or P/NP)
Course study under this section may be repeated three times for a maximum of 5 units.
Acceptable for credit: CSU
Description: See section on Independent Study. 0430.00
 

Course Number: BIOSC 50
Genetic Diseases
Units: 4
Class:  4 hours lecture (GR or P/NP)
Acceptable for credit: CSU
Description: Survey of common genetic diseases which result from various mutations and chromosomal aberrations: Genetic modifiers and epigenetic factors as they relate to disease; review of basic Mendelian principles.  0430.00
 

Course Number: BIOSC 51
Medical Genomics
Units: 3
Class:  3 hours lecture (GR or P/NP)
Recommended preparation: Biol 10
Acceptable for credit: CSU
Description: Survey of current trends in human genome study: Gene theory, potential and current treatment of human genetic diseases, ethics in science, the effect of next-generation sequencing on the human genome, and the effect human genomics will have on society in the future.  0430.00
 

Course Number: BIOSC 60
Post-Light Sequencing on the Ion Torrent DNA Sequencer
Units: 2
Class:  2 hours lecture, 3 hours laboratory (GR or P/ NP)
Pre-requisite: Biosc 38 and 40 and 41
Acceptable for credit: CSU
Description: Ion-torrent technology and applications: Set-up for instrument operation, techniques for library creation, sample preparation, instrument operation and data analysis.  0430.00
 

Course Number: BIOSC 61
Sequence Analysis Using MacVector
Units: 1
Class:  1 hour lecture (GR or P/NP)
Recommended preparation: CIS 1
Acceptable for credit: CSU
Description: Proficiency in using MacVector software: Mining GenBank and preparation of GenBank files, clustal alignments, gene annotation, and frame orientation of protein-coding genes. 0430.00
 

Course Number: BIOSC 62
Methodologies in Phylogenetics Using PAUP
Units: 1
Class:  1 hour lecture (GR)
Acceptable for credit: CSU
Description: Introduction to PAUP software: Character vs. character states, parsimony, distance and the methods, shared ancestry vs. homoplasy (reversals vs. parallelisms).  0430.00
 

Course Number: BIOSC 63
Introduction to Character Tracing Using MacClade
Units: 1
Class:  1 hour lecture (GR)
Acceptable for credit: CSU
Description: Introduction to MacClade software: Evolution of alternative character states and visual interface for phylogenetic trees.  0430.00
 

Course Number: BIOSC 72
DNA Sequencing Using Bridge Amplification for the Illumina HiSeq
Units: 3
Class:  2 hours lecture, 3 hours laboratory (GR)
Acceptable for credit: CSU
Description: DNA sequencing with the Illumnia High Seq: Techniques in bridge amplification, sample preparations and troubleshooting.  0430.00
 

Course Number: BIOSC 90
Internship in Genomics
Units: 3
Class:  .1 hour lecture, 6 hours laboratory (GR or P/NP)
Pre-requisites: Biosc 30, Biosc 31, Biosc 32
Acceptable for credit: CSU
Description: Study of the specific competencies required in the Genomics Internship program: Assessment, development, practicum, and evaluation of individual skills in a genomics work setting. 0430.00